Endocrine Abstracts

Multiple endocrine neoplasia 2A (MEN2A), an autosomal dominant genetic syndrome caused by germline mutation in RET proto-oncogene, associates medullary thyroid carcinoma (MTC), pheochromocytoma (PHEO) and primary hyperparathyroidism (HPT). Thyroid hemiagenesis (TH), the absence of one lobe, is a rare congenital abnormality (300 cases are reported in literature). Most cases of TH are diagnosed when patients present a lesion in the functioning lobe. TH was observed among members...

Parathyroid adenomas (85% of cases of primary hyperparathyroidism) are usually small in size (weigh 70 mg – 1 g). Giant parathyroid adenomas (GPTA) weighing more than 3.5 g are very rare, more common in males, in the 6th decade of life, generally affect one parathyroid gland, are oxyphilic and ectopic in 50% of cases.We report the case of a 53-year-old woman presented for asthenia, fatigue, tingling in the arms and legs without other symp...